Gregory H. Babunovic

Harvard T.H. Chan School of Public Health - Department of Immunology and Infectious Diseases

Cambridge, MA

United States

  • Harvard T.H. Chan School of Public Health - Department of Immunology and Infectious Diseases

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High-Throughput CRISPR Screens to Dissect Macrophage- Shigella Interactions

Number of pages: 61 Posted: 07 Dec 2020
Yong Lai, Liang Cui, Gregory H. Babunovic, Sarah M. Fortune, John G. Doench and Timothy K. Lu
Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Harvard T.H. Chan School of Public Health - Department of Immunology and Infectious Diseases, Harvard University - Ragon Institute of MGH, MIT and Harvard, Broad Institute and Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group
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Abstract:

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Host-pathogen interactions, shigellosis, host-directed therapy, CRISPR-Cas9 knockout screen, CRISPRi screen, macrophage, TLR1/2 signaling, pyruvate catabolism