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Jiannan Feng

Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures

Beijing

China

SCHOLARLY PAPERS

5

DOWNLOADS

231

TOTAL CITATIONS

1

Scholarly Papers (5)

1.

Screening and Identification of a Novel Anti-siglec-15 Human Antibody 3F1 and the Research on Its Antitumor Activity

Number of pages: 35 Posted: 28 Oct 2021
Dali University - Department of Anatomy, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Hunan Normal University - School of Medicine, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Henan University - Joint National Laboratory for Antibody Drug Engineering, Government of the People's Republic of China - Department of Obstetrics and Gynecology, Dali University - Department of Anatomy and Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures
Downloads 96

Abstract:

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siglec-15, immune checkpoint molecules, tumor immunotherapy, human phage antibody library, ligands

2.

Acid-Driven Immune Suppression by pHLIP-Fused PD-L1 Under Inflammatory Conditions

Number of pages: 27 Posted: 24 Oct 2023
Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Inner Mongolia Medical University, Academy of Military Medical Sciences, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Inner Mongolia Medical University, Chinese PLA General Hospital, Inner Mongolia Medical University and Academy of Military Medical Sciences
Downloads 53

Abstract:

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PD-L1, pHLIP;Acid environment, DSS colities, Macrophage

3.

Benchmarking Antibody Modeling Tools across Structure Prediction, Docking, and Paratope–Epitope Interface Analysis

Number of pages: 41 Posted: 11 Jun 2025 Last Revised: 15 Jun 2026
affiliation not provided to SSRN, Jiangsu University of Science and Technology, Qingdao University, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Academy of Military Medical Sciences, affiliation not provided to SSRN, affiliation not provided to SSRN, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures and affiliation not provided to SSRN
Downloads 36

Abstract:

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antibody structure prediction, antigen–antibody docking, paratope–epitope interface, benchmarking, AlphaFold3

4.

Rack1 is Essential for Corticogenesis by Preventing P21-Dependent Senescence in Neural Stem Cells

Number of pages: 72 Posted: 22 Dec 2020
Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neurobiology, Beijing Institute of Basic Medical Sciences - Department of Neuroimmunology and Antibody Engineering, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Basic Medical Sciences - Department of Neurobiology and Beijing Institute of Basic Medical Sciences - Department of Neurobiology
Downloads 34
Citation 1

Abstract:

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microcephaly; Rack1; neural stem cells; cellular senescence; p21; TGF-β/Smad

5.

The pan-filovirus activity of an IGF2-fused monoclonal antibody is impaired by cross-engagement with IGF1R which is improved by introducing Y27L mutation in IGF2

Number of pages: 45 Posted: 04 Apr 2026
Academy of Military Medical Sciences, Jiangsu University of Science and Technology, Henan University, Academy of Military Medical Sciences, Shenyang Pharmaceutical University, Shenyang Pharmaceutical University, Shenyang Pharmaceutical University, Shenyang Pharmaceutical University, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures, Academy of Military Medical Sciences, Academy of Military Medical Sciences, Government of the People's Republic of China - Division of HIV/AIDS and Sex-transmitted Virus Vaccines, WHO Collaborating Center for Standardization and Evaluation of Biologicals, Academy of Military Medical Sciences, Institute of Pharmacology and Toxicology - State Key Laboratory of Toxicology and Medical Countermeasures and Jiangsu University of Science and Technology
Downloads 12

Abstract:

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Filoviruses, Neutralizing antibody, IGF1R, IGF2R