Imperial College London - Department of Paediatrics, Mulago National Referral Hospital, Busitema University - Mbale Clinical Research Institute, University of Oxford - KEMRI-Coast Centre for Geographical Medicine and Research, Intensive Care National Audit & Research Centre, Soroti Regional Referral Hospital, Mulago Regional Referral Hospital, Jinja Regional Referral Hospital, Coast General District Hospital, Kenya Medical Research Institute (KEMRI)– Wellcome Trust Research Programme, Kilifi County Hospital, Mulago Regional Referral Hospital, Busitema University - Mbale Clinical Research Institute, Soroti Regional Referral Hospital, Soroti Regional Referral Hospital, Soroti Regional Referral Hospital, Kenya Medical Research Institute (KEMRI), Coast General District Hospital, Kenya Medical Research Institute (KEMRI) - Kemri-Wellcome Trust Research Programme, Intensive Care National Audit & Research Centre and Intensive Care National Audit & Research Centre