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Pak-Chung Sham

The University of Hong Kong - Department of Psychiatry

SCHOLARLY PAPERS

5

DOWNLOADS

260

TOTAL CITATIONS

1

Scholarly Papers (5)

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1.

Development of a Machine Learning Polyvariant Risk Prediction Model for Severe Cutaneous Adverse Drug Reactions to Carbamazepine and Other Aromatic Antiseizure Medications

Number of pages: 20 Posted: 09 Nov 2024
Robert Zeibich, Alison Anderson, Zhibin Chen, Yi-wu Shi, Ching-Ching Ng, Larry Baum, Stacey Cherny, Pak-Chung Sham, Kheng Seang Lim, Wei-Ping Liao, Terence J. O’Brien, Piero Perucca and Patrick Kwan
Monash University, Monash University, Monash University, Guangzhou Medical University - Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province (MOE), The University of Hong Kong, Guangzhou Medical University, The University of Hong Kong, The University of Hong Kong - Department of Psychiatry, University of Malaya (UM) - Department of Medicine, Guangzhou Medical University, Monash University, University of Melbourne and Monash University - Department of Neuroscience
Downloads 119 (613,149)

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Machine Learning, Bootstrapping, Transcription Factor Binding, Expression Quantitative Trait Loci (eQTL), Carbamazepine (CBZ), Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), Positive Predictive Value (PPV)

2.

Identification of a Wide Spectrum of Ciliary Gene Mutations in Nonsyndromic Biliary Atresia Patients Implicates Ciliary Dysfunction as a Novel Disease Mechanism

Number of pages: 35 Posted: 18 Feb 2021
Wai-Yee Lam, Clara S. Tang, Man-Ting So, Jacob Shujui Hsu, Patrick Ho-Yu Chung, John M. Nicholls, Fanny Yeung, Chun-Wai Davy Lee, Diem Ngoc Ngo, Pham Anh Hoa Nguyen, Hannah M. Mitchison, Dagan Jenkins, Christopher O’Callaghan, Maria-Mercè Garcia-Barceló, So-Lun Lee, Vincent CH Lui, Pak-Chung Sham and Paul KH Tam
The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Psychiatry, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Pathology, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Paediatrics, National Hospital of Pediatrics, Vietnam, National Hospital of Pediatrics, Vietnam, University College London - Genetics and Genomic Medicine, University College London - Genetics and Genomic Medicine, University College London - Respiratory, Critical Care & Anaesthesia Section, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Paediatrics, The University of Hong Kong - Department of Surgery, The University of Hong Kong - Department of Psychiatry and The University of Hong Kong - Department of Surgery
Downloads 43 (1,145,425)
Citation 1

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Biliary atresia; whole exome sequencing; rare variants; cilia dysfunction

3.

Obstetric and Neonatal Complications at Birth Increased Risk of Developing Neurodevelopmental Disorders in Childhood or Adolescence: A Population-Based Cross-Generation Birth-Cohort Study

Number of pages: 29 Posted: 02 Feb 2026
Perry B.M. Leung, Jinghong Qiu, Ka-Wang Cheung, Na Zhan, Kenneth CY Wong, Yuanxin Zhong, Evangelos Vassos, Marta Di Forti, Robin Murray, Hon-Cheong So, Pak-Chung Sham and Simon S. Y. LUI
The University of Hong Kong, The Chinese University of Hong Kong (CUHK), The University of Hong Kong, The University of Hong Kong, The Chinese University of Hong Kong (CUHK), The University of Hong Kong, King’s College London - Social, Genetic and Developmental Psychiatry Centre, King’s College London - Social, Genetic and Developmental Psychiatry Centre, King’s College London - Department of Psychosis Studies, The Chinese University of Hong Kong (CUHK), The University of Hong Kong - Department of Psychiatry and The University of Hong Kong
Downloads 40 (1,209,354)

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Neurodevelopmental disorders, obstetric complications, electronic health record, survival analysis, sibling-matched analysis

4.

Rare Variants May Influence Disease Risk and Clinical Features in Sporadic Late-Onset Chinese Parkinson's Disease Patients

Number of pages: 24 Posted: 08 Jul 2025
Ryan Wui-Hang Ho, Zewei Xiong, Rachel Cheuk-Nam Lo, Huifang Liu, Philip Wing-Lok Ho, Pak-Chung Sham, Shu-Leong Ho and Shirley Yin-Yu Pang
The University of Hong Kong, The University of Hong Kong, The University of Hong Kong, Hong Kong Polytechnic University, Hong Kong Polytechnic University, The University of Hong Kong - Department of Psychiatry, The University of Hong Kong and The University of Hong Kong
Downloads 33 (1,277,121)

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parkinson's, Genetics, genotype-phenotype, rare variants

5.

Family-based whole genome sequencing identifies de novo variants in potassium channel genes for attention-deficit/hyperactivity disorder

Number of pages: 28 Posted: 19 Mar 2026
Yuanxin Zhong, Rui Ye, Larry Baum, Justin D. Tubbs, Se-Fong Hung, Chun-Pan Tang, Ting-Pong Ho, Chi-Chiu Lee, Pak-Chung Sham and Patrick Wing-Leung Leung
The University of Hong Kong, The University of Hong Kong, The University of Hong Kong, The University of Hong Kong - Department of Psychiatry, The Chinese University of Hong Kong, affiliation not provided to SSRN, The University of Hong Kong, affiliation not provided to SSRN, The University of Hong Kong - Department of Psychiatry and The Chinese University of Hong Kong
Downloads 25 (1,481,165)

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family-based, WGS, de novo variants, ADHD, potassium channel