Tianjin Medical University - Department of Thyroid and Neck Tumor, Tianjin Medical University - Department of Thyroid and Neck Tumor, Tianjin Medical University - Department of Thyroid and Neck Tumor, Tianjin First Center Hospital - Department of Otolaryngology-Head and Neck Surgery, Tianjin First Center Hospital - Department of Otolaryngology-Head and Neck Surgery, Tianjin Medical University - Department of Thyroid and Neck Tumor, Sanford Burnham Prebys Medical Discovery Institute - Cancer Metabolism and Signaling Networks Program, University of Wisconsin-Madison - Department of Medical Genetics, Tianjin Medical University - Department of Thyroid and Neck Tumor, Tianjin Medical University - Department of Thyroid and Neck Tumor and Tianjin Medical University - National Clinical Research Center for Cancer