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Hirotsugu Ishizu

Keio University - Department of Molecular Biology

2-15-45 Mita

Minato-ku

Tokyo, 108-8345

Japan

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Scholarly Papers (1)

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Pro108Ser mutant of SARS-CoV-2 3CL pro Reduces the Enzymatic Activity and Ameliorates COVID-19 Severity in Japan

Number of pages: 25 Posted: 30 Dec 2020
Kodai Abe, Yasuaki Kabe, Susumu Uchiyama, Yuka W.Iwasaki, Hirotsugu Ishizu, Yoshifumi Uwamino, Toshiki Takenouchi, Shunsuke Uno, Makoto Ishii, Takahiro Maruno, Masanori Noda, Mitsuru Murata, Naoki Hasegawa, Hideyuki Saya, Yuko Kitagawa, Koichi Fukunaga, Masayuki Amagai, Haruhiko Siomi, Makoto Suematsu, Kenjiro Kosaki and Keio Donner Project
Keio University - Department of Surgery, Keio University - Department of Biochemistry, Osaka University - Department of Biotechnology, Keio University - Department of Molecular Biology, Keio University - Department of Molecular Biology, Keio University - Division of Infection Diseases and Infection Control, Keio University - Department of Pediatrics, Keio University - Department of Infectious Diseases, Keio University - School of Medicine, Osaka University - Department of Biotechnology, U-Medico, Inc., Keio University - Department of Laboratory Medicine, Keio University, School of Medicine, Center for Infectious Diseases and Infection Control, Keio University - Division of Gene Regulation, Keio University - Department of Surgery, Keio University - Division of Pulmonary Medicine, Keio University - Department of Dermatology, Keio University - Department of Molecular Biology, Keio University - Department of Biochemistry, Keio University - Center for Medical Genetics and Independent
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Abstract:

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SARS-CoV-2, COVID-19, non-synonymous mutation, 3CLpro, Pro108Ser