University of Birmingham - Institute of Cardiovascular Sciences, University of Birmingham - Institute of Cardiovascular Sciences, University of Barcelona - Institut Clínic Cardiovascular (ICCV), Ludwig Maximilian University of Munich (LMU) - Department of Medicine I, University of Birmingham - Institute of Cardiovascular Sciences, University of Oxford, Maastricht University - Cardiovascular Research Institute Maastricht (CARIM), Maastricht University - Cardiovascular Research Institute Maastricht (CARIM), IHU-ICAN Institute of Cardiometabolism and Nutrition, Ludwig Maximilian University of Munich (LMU) - Department of Medicine I, Roche Diagnostics GmbH, University of Barcelona - Institut Clínic Cardiovascular (ICCV), University of Birmingham - Institute of Cardiovascular Sciences, University of Birmingham - Institute of Cardiovascular Sciences, University of Birmingham - Institute of Cardiovascular Sciences, Maastricht University - Cardiovascular Research Institute Maastricht (CARIM), Maastricht University - Cardiovascular Research Institute Maastricht (CARIM), Roche Diagnostics International AG, University of Birmingham, University of Birmingham - Institute of Cardiovascular Sciences and University of Birmingham - Institute of Cardiovascular Sciences