Juliet Keidan Institute of Pediatric Gastroenterology Hepatology and Nutrition, Hebrew University of Jerusalem - Shaare Zedek Medical Center, Maccabi Health Services, Tel-Aviv, Israel and the Sackler Faculty of Medicine, Meuhedet Health Services, Maccabi Health Services, Tel-Aviv, Israel and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv University - Sackler Faculty of Medicine, Ben Gurion University of the Negev, Chaim Sheba Medical Center - The Oncogenetics Unit, Leumit Health Services, Tel Aviv University - Rabin Medical Center, Department of Gastroenterology, Rambam Healthcare Campus, Hebrew University of Jerusalem - Shaare Zedek Medical Center, Hebrew University of Jerusalem - Shaare Zedek Medical Center and Hebrew University of Jerusalem - Juliet Keidan Institute of Pediatric Gastroenterology Hepatology and Nutrition