University of Oxford - Oxford Vaccine Group, University of Siena - Institute of Global Health, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Federal University of São Paulo (UNIFESP), University of Oxford - The Jenner Institute, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - Oxford Vaccine Group, University of the Witwatersrand, Stellenbosch University - Family Centre for Research with Ubuntu, Soweto Clinical Trials Centre, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of Oxford - The Jenner Institute, University of Oxford - Centre for Vaccinology and Tropical Medicine, Liverpool School of Tropical Medicine - Department of Clinical Sciences, University of the Witwatersrand - South African Medical Research Council Vaccines and Infectious Diseases Analytical Research Unit, University of Sheffield - Department of Infection, Immunity and Cardiovascular Disease, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, University of Oxford - Jenner Institute, Newcastle upon Tyne Hospitals NHS Foundation Trust - Department of Infection and Tropical Medicine, University of Oxford - Oxford Vaccine Group, GSK plc, University of Oxford - The Jenner Institute, Wits Reproductive Health & HIV Institute (WRHI), University of Southampton - NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University of Oxford - Oxford Vaccine Group, University of Liverpool - School of Tropical Medicine, University of Bristol - Bristol Vaccine Centre, St George’s University London - St George’s Vaccine Institute, University College London - Department of Infection, University of Oxford - Clinical BioManufacturing Facility, University Hospitals Birmingham NHS Foundation Trust, University of Oxford - Oxford Vaccine Group, University of the Witwatersrand - South African Medical Research Council, Liverpool School of Tropical Medicine - Department of Clinical Sciences, AstraZeneca Pharmaceuticals, University of the Witwatersrand - South African Medical Research Council, University of Oxford - The Jenner Institute, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of the Witwatersrand - South African Medical Research Council, University of the Witwatersrand - South African Medical Research Council, University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, University College London, Hull University Teaching Hospitals NHS Trust, University of Oxford - Centre for Vaccinology and Tropical Medicine, AstraZeneca Pharmaceuticals, Braziland Hospital São Rafael - Escola Bahiana de Medicina e Saúde Pública, Universidade Federal do Rio Grande do Norte (UFRN), University of Oxford - The Jenner Institute, London Northwest University Healthcare, University of Oxford - Oxford Vaccine Group, University of the Witwatersrand - Perinatal HIV Research Unit, Setshaba Research Centre, University of Oxford - Oxford Vaccine Group, Hospital Quinta D'OR, University of Oxford - Oxford Vaccine Group, Imperial College London - Department of Infectious Disease, University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, Hospital Universitário de Santa Maria, University of Glasgow - College of Medical, Veterinary & Life Sciences, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - Centre for Vaccinology and Tropical Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Western General Hospital - Clinical Infection Research Group, MRC-University of Glasgow Centre for Virus Research, University of Cambridge - Department of Medicine, Royal Papworth HospitalUniversity of Cambridge - Heart and Lung Research Institute, Nottingham University Hospitals NHS Trust, AstraZeneca Biopharmaceuticals, AstraZeneca Pharmaceuticals, AstraZeneca Pharmaceuticals, Anuerin Bevan University Health Board, University of Oxford - The Jenner Institute, University of Oxford - The Jenner Institute, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group and Independent

Universidad Europea de Madrid - Paediatrics Research Group, Instituto de Investigación 12 de Octubre (imas12) - Pediatric Infectious Diseases Unit, Stellenbosch University - Children’s Infectious Diseases Clinical Research Unit (KID-CRU), University of the Witwatersrand, University College London - Infection, Immunity and Inflammation Research & Teaching Department, Fundação Ariel Glaser contra o SIDA Pediatrico, Centro de Investigação em Saúde da Manhiça (CISM), Centre Hospitalier Universitaire Gabriel Touré, Stellenbosch University - Family Centre for Research with Ubuntu, Fundação Ariel Glaser contra o SIDA Pediatrico, University of the Witwatersrand - Perinatal HIV Research Unit, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Africa Health Research Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Stellenbosch University, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Africa Health Research Institute, Africa Health Research Institute, University of North Carolina (UNC) at Chapel Hill - National Institute of Health, University of Padua - Department of Women’s and Children’s Health, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Columbia University - Irving Medical Center, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), University College London Hospitals NHS Foundation Trust - Advanced Pathogen Diagnostics Unit, Ragon Institute of MGH, MIT and Harvard, University College London Hospitals NHS Foundation Trust - Advanced Pathogen Diagnostics Unit, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), affiliation not provided to SSRN, affiliation not provided to SSRN, Stellenbosch University, Stellenbosch University, Africa Health Research Institute, Imperial College London - Department of Paedaitric Infectious Diseases, Stellenbosch University, Baylor College of Medicine, affiliation not provided to SSRN, University of Miami - Miami Center for AIDS Research, affiliation not provided to SSRN, University Hospital 12 de Octubre and Independent

University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, National Institute For Communicable Diseases Of South Africa - Division of Public Health Surveillance and Response, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand - Faculty of Health Sciences, University of the Witwatersrand - Reproductive Health and HIV Research Unit (RHRU), Setshaba Research Centre, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, Stellenbosch University - Family Centre for Research with Ubuntu, Soweto Clinical Trials Centre, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Setshaba Research Centre, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, Soweto Clinical Trials Centre, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, University of the Witwatersrand, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, Setshaba Research Centre, National Institute for Communicable Diseases of the National Health Laboratory Service, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, National Health Laboratory Services (NHLS) - National Institute for Communicable Diseases, University of Cape Town (UCT) - Centre for Lung Infection and Immunity, University of the Witwatersrand, Guy's and St Thomas' NHS Foundation Trust - Department of Infection, University of the Witwatersrand - Reproductive Health and HIV Research Unit (RHRU), University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of the Witwatersrand and University of the Witwatersrand - Vaccines and Infectious Diseases Analytics Research Unit

Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Bambino Gesù Children's Hospital, Instituto de Investigación 12 de Octubre (imas12) - Pediatric Infectious Diseases Unit, University of Padua, Universidad Europea de Madrid - Paediatrics Research Group, Columbia University - Irving Medical Center, Stellenbosch University - Children’s Infectious Diseases Clinical Research Unit (KID-CRU), University of the Witwatersrand, University of Padova, Fundação Ariel Glaser contra o SIDA Pediatrico, Stellenbosch University - Family Centre for Research with Ubuntu, University College London Hospitals NHS Foundation Trust - Advanced Pathogen Diagnostics Unit, University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), University of Barcelona - Institut de Salut Global de Barcelona (ISGlobal), Centro de Investigação em Saúde da Manhiça (CISM), Centre Hospitalier Universitaire Gabriel Touré, University of Sciences, Technique and Technologies of Bamako (USTTB), Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), University Hospital 12 de Octubre, University of Padua - Department of Women’s and Children’s Health, Ragon Institute of MGH, MIT and Harvard, University of the Witwatersrand - Perinatal HIV Research Unit, Africa Health Research Institute, Africa Health Research Institute, Africa Health Research Institute, University of Miami - Miami Center for AIDS Research, University of Miami - Miami Center for AIDS Research, Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO), Bambino Gesù Children's Hospital - Academic Department of Pediatrics (DPUO) and Independent