Columbia University - Department of Systems Biology, Sage Bionetworks - Computational Oncology Group, Semmelweis University - Department of Physiology, University of Helsinki - Research Program in Systems Oncology, Tsinghua University - Institute for Interdisciplinary Information Sciences, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Columbia University - Department of Systems Biology, Columbia University - Department of Systems Biology, University of Helsinki - Research Program in Systems Oncology, Institute for Molecular Medicine Finland (FIMM) - Metabolomics Unit, University of Helsinki - Research Program in Systems Oncology, University of Helsinki - Research Program in Systems Oncology, Tsinghua University - Institute for Interdisciplinary Information Sciences, Tsinghua University - Institute for Interdisciplinary Information Sciences, Tsinghua University - Department of Computer Science and Technology, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, Sage Bionetworks - Computational Oncology Group, Independent, University of Helsinki - Research Program in Systems Oncology, Tsinghua University - Institute for Interdisciplinary Information Sciences, Barcelona Institute of Science and Technology (BIST) - Joint IRB-BSC-CRG Program in Computational Biology, RWTH Aachen University - Joint Research Center for Computational Biomedicine, Sage Bionetworks - Computational Oncology Group, National Institutes of Health (NIH) - Office of Cancer Genomics and Columbia University Irving Medical Center - Department of Systems Biology