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Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Birmingham - Clinical Immunology Service, University of Birmingham - Institute of Cancer and Genomic Science, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity and Cardiovascular Disease, Public Health England Colindale, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Wellcome Centre for Human Genetics, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Sheffield Teaching Hospitals NHS Foundation Trust, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford, University Hospitals Birmingham NHS Foundation Trust, Public Health England Colindale, Public Health England Colindale, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Peter Medawar Building for Pathogen Research, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, Oxford University Hospitals NHS Foundation Trust, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, University of Oxford - Peter Medawar Building for Pathogen Research, Sheffield Teaching Hospitals NHS Foundation Trust, University of Oxford - Wellcome Trust Centre for Human Genetics, Oxford University Hospitals NHS Foundation Trust, University of Oxford - NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, Public Health England Colindale, Newcastle upon Tyne Hospitals NHS Foundation Trust - Department of Infection and Tropical Medicine, University of Birmingham - Institute of Cancer and Genomic Sciences, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research and Independent

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Queen Mary University of London - Blizard Institute, University of Birmingham - Clinical Immunology Service, Queen Mary University of London - Institute of Population Health Sciences, Queen Mary University of London, Queen Mary University of London, Queen Mary University of London - Institute of Population Health Sciences, Queen Mary University of London, Queen Mary University of London - Centre for Immunobiology, Queen Mary University of London, Jane Symons Media, Swansea University - Swansea University Medical School, Swansea University - Population Data Science, Queen Mary University of London - Asthma UK Centre for Applied Research, Queen's University Belfast, University of Edinburgh - Usher Institute, Queen Mary University of London - Institute of Population Health Sciences, University of Birmingham - Institute of Cancer and Genomic Sciences and Queen Mary University of London - Barts and The London School of Medicine and Dentistry

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University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Oxford Vaccine Group, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Birmingham - Clinical Immunology Service, University of Birmingham - Institute of Cancer and Genomic Science, University of Oxford - Pandemic Sciences Institute, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Liverpool - NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, NHS Foundation Trust - Liverpool University Hospitals NHS Foundation Trust (LUH), Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Dept Infection, Immunity & Cardiovascular Disease, University of Sheffield, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, Dept of Infectious Diseases & Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Newcastle Upon Tyne Hospitals NHS Foundation Trust - Department of Infection and Tropical Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Birmingham - Institute of Immunology and Immunotherapy, University of Cambridge - MRC Toxicology Unit, University of Cambridge - MRC Toxicology Unit, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation Trust, Oxford University Hospitals NHS Foundation Trust, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Oxford Vaccine Group, University of Oxford - Peter Medawar Building for Pathogen Research, Sheffield Teaching Hospitals NHS Foundation Trust, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Newcastle University - Translational and Clinical Research Institute Immunity and Inflammation Theme, University of Oxford - Oxford Vaccine Group, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Cambridge - MRC Toxicology Unit, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - NIHR Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance, Public Health England Colindale, Newcastle University - Translational and Clinical Research Institute, University of Birmingham - Institute of Cancer and Genomic Sciences, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Sheffield - Department of Infection, Immunity & Cardiovascular Disease, University of Oxford - Nuffield Department of Clinical Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Liverpool - NIHR Health Protection Research Unit for Emerging and Zoonotic Infection and Independent