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Sean J. Morrison

University of Texas Southwestern Medical Center - Children’s Research Institute

2601 North Floyd Road

Richardson, TX 75083

United States

  • University of Texas Southwestern Medical Center - Children’s Research Institute

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Hematopoietic Stem Cells Self-Renew Symmetrically or Gradually Proceed to Differentiation

Number of pages: 49 Posted: 18 Feb 2021
Melania Barile, Katrin Busch, Ann-Kathrin Fanti, Alessandro Greco, Xi Wang, Hideyuki Oguro, Qin Zhang, Sean J. Morrison, Hans-Reimer Rodewald and Thomas Höfer
Deutsches Krebsforschungszentrum - Division of Theoretical Systems Biology, Deutsches Krebsforschungszentrum - Division of Cellular Immunology, Deutsches Krebsforschungszentrum - Division of Cellular Immunology, Deutsches Krebsforschungszentrum - Division of Theoretical Systems Biology, Deutsches Krebsforschungszentrum - Division of Theoretical Systems Biology, University of Connecticut - Department of Cell Biology, Deutsches Krebsforschungszentrum - Division of Theoretical Systems Biology, University of Texas Southwestern Medical Center - Children’s Research Institute, Deutsches Krebsforschungszentrum - Division of Cellular Immunology and Deutsches Krebsforschungszentrum - Division of Theoretical Systems Biology
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Abstract:

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hematopoiesis, self-renewal, stem cell differentiation, stem cell heterogeneity, fate mapping, single-cell RNA sequencing, mathematical modeling, statistical inference