Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Fudan University - Department of Endocrinology and Metabolism, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, East China Normal University (ECNU) - Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Shanghai Jiao Tong University (SJTU) - Department of Bioinformatics and Biostatistics, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, East China Normal University (ECNU) - Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University (ECNU) - Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research, Shanghai Jiao Tong University (SJTU) - Department of Bioinformatics and Biostatistics, Fudan University - Department of Endocrinology and Metabolism, Fudan University - Department of Endocrinology and Metabolism, Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research and Chinese Academy of Sciences (CAS) - State Key Laboratory of Drug Research