affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Università degli Studi di Bari “Aldo Moro” (UNIBA), affiliation not provided to SSRN, Humanitas Gavazzeni, University of Parma, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Ferrara, affiliation not provided to SSRN, Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) - IRCCS Veneto Institute of Oncology (IOV-IRCCS), affiliation not provided to SSRN, affiliation not provided to SSRN, University of Padova - Department of Cardiac, Thoracic, Vascular Science and Public Health, affiliation not provided to SSRN, affiliation not provided to SSRN and affiliation not provided to SSRN