University of Ottowa - Children’s Hospital of Eastern Ontario, University of Toronto - The Hospital for Sick Children, Pediatric Hospital Bambino Gesù - Pediatric Hematology/Oncology Department, Baylor College of Medicine - Department of Pediatrics, Royal Hospital for Children, University of Alberta - Department of Pediatrics, Kazan Medical University - Pediatric Hospital, University of Iowa Carver College of Medicine - Stead Family Department of Pediatrics, Municipal Children’s Hospital (Morozovskaya) - Pediatric Hematology Department, Tyumen Regional Hospital #1 - Pediatric Cardiovascular Surgery, Boehringer Ingelheim International GmbH - Cardiovascular Medicine, Boehringer Ingelheim RCV GmbH & Co - Department of Clinical Development, Boehringer Ingelheim Pharmaceuticals, Inc. - Translational Medicine and Clinical Pharmacology-, Boehringer Ingelheim Pharmaceuticals, Inc. - Biostatistics and Data Sciences -, Boehringer Ingelheim Singapore Pte. Ltd, Boehringer Ingelheim International GmbH - Therapeutic Area Inflammation Medicine, Boehringer Ingelheim Pharmaceuticals, Inc. - Therapeutic Area Cardiovascular Medicine, University of Heidelberg - Faculty of Medicine Mannheim, University of Zurich - Hematology Department and Independent