King’s College London - Centre for Host-Microbiome Interactions, Royal Institute of Technology (KTH) - Science for Life Laboratory (SciLife Lab), AstraZeneca Pharmaceuticals - IMED Biotech Unit, AstraZeneca Pharmaceuticals - Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), AstraZeneca Pharmaceuticals - IMED Biotech Unit, University of Gothenburg - Department of Molecular and Clinical Medicine, University of Gothenburg - Department of Molecular and Clinical Medicine, Royal Institute of Technology (KTH) - Science for Life Laboratory (SciLife Lab) and University of Gothenburg - Department of Molecular and Clinical Medicine