Icahn School of Medicine - Zena and Michael A. Weiner Cardiovascular Institute, Mount Sinai Health System - Mindich Child Health and Development Institute, Mount Sinai Health System - Charles Bronfman Institute for Personalized Medicine, Mount Sinai Health System - Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai - Icahn Institute for Data Science and Genomic Technology, Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Saarland University Medical Center - Department of Internal Medicine III (Cardiology, Angiology and Intensive Care), Saarland University Medical Center - Department of Internal Medicine III (Cardiology, Angiology and Intensive Care), University of Tennessee, Memphis - Department of Pediactrics, Saarland University Medical Center - Department of Internal Medicine III (Cardiology, Angiology and Intensive Care), University of Tuebingen - Department of Cardiopathology and Icahn School of Medicine at Mount Sinai - Department of Genetics and Genomic Sciences, Mindich Child Health and Development Institute, and Department of Pediatrics