University of Oxford - Nuffield Department of Medicine, Government of the United States of America - Frederick National Laboratory for Cancer Research, Government of the United States of America - Laboratory of Translational Genomics, Harvard University - Division of Population Sciences, Harvard University - Massachusetts General Hospital, Harvard University - Lank Center for Genitourinary Oncology, Harvard University - Massachusetts General Hospital, Government of the United States of America - Frederick National Laboratory for Cancer Research, EMD Serono Research & Development Institute - Bioinformatics, Department of Translational Medicine, Harvard University - Dana-Farber Cancer Institute, Bristol Myers Squibb, Pfizer, Inc. - Computational Biology, Pfizer, Inc. - Translational Oncology, Harvard University - Division of Population Sciences, Harvard University - Lank Center for Genitourinary Oncology, National Institutes of Health (NIH) - Clinical Immunotherapy Section and National Cancer Institute - Basic Science Program