China Agricultural University - State Key Laboratory of Agrobiotechnology, University of California, Irvine - NSF-Simons Center for Multiscale Cell Fate Research, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, China Agricultural University - State Key Laboratory of Agrobiotechnology, Central South University - Department of Gastroenterology, Central South University - Department of Gastroenterology, Fourth Military Medical University - Department of Gastroenterology, China Agricultural University - Beijing Advanced Innovation Center for Food Nutrition and Human Health, University of California, Irvine - NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine - NSF-Simons Center for Multiscale Cell Fate Research, China Agricultural University - Beijing Advanced Innovation Center for Food Nutrition and Human Health and China Agricultural University - Key Laboratory of Precision Nutrition and Food Quality