Kyushu University - Department of Medicine, Kyushu University - Department of Medicine, Kyushu University - Department of Medicine, Kobe University - Division of Bioregulation, Kyushu University - Department of Medicine, Kobe University - Division of Bioregulation, Kobe University - Division of Bioregulation, Kobe University - Division of Bioregulation, Kobe University - Division of Bioregulation, Kobe University - Division of Bioregulation, Kobe University - Division of Bioregulation, Kobe University Graduate School of Health Sciences - Division of Bioregulation, Kobe University - Division of Bioregulation, Kyushu University - Department of Medicine, Matsubara Mayflower Hospital - Department of Medicine, Rheumatology and Orthopedic Surgery, Oribe Clinic, Kakogawa City Hospital - Department of Rheumatology, Red Cross Society Himeji Hospital - Department of Medicine, University of Texas Southwestern Medical Center - Department of Immunology, KAN Research Institute, Inc. - Drug Discovery Platform, KAN Research Institute, Inc. - Drug Discovery Platform, Tohoku Medical and Pharmaceutical University, Kindai University - Department of Immunology, Kindai University - Department of Immunology, Kindai University - Department of Immunology, Kindai University - Department of Immunology and Hyogo Prefectural Kakogawa Medical Center - Rheumatology and Collagen Disease Center