Uppsala University - Department of Immunology, Genetics and Pathology, Clinical and Experimental Oncology, Uppsala University - Department of Immunology, Genetics and Pathology, Clinical and Experimental Oncology, Uppsala University - Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University - Department of Immunology, Genetics and Pathology, Clinical and Experimental Oncology, Uppsala University - Department of Immunology, Genetics and Pathology, Clinical and Experimental Oncology, AstraZeneca R&D - Translational Science & Experimental Medicine, University of Copenhagen, Uppsala University - Science for Life Laboratory, University of Copenhagen - The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen - Novo Nordisk Foundation Center for Protein Research, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Medical Sciences, Clinical Diabetes and Metabolism and Uppsala University - Department of Immunology, Genetics and Pathology, Clinical and Experimental Oncology