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Wen Luo

McGill University - McGill Parkinson Program and Neurodegenerative Diseases Group

1001 Sherbrooke St. W

Montreal, Quebec H3A 1G5

Canada

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Optogenetic-Mediated Spatiotemporal Control of α-Synuclein Aggregation Mimics Lewy Body Formation and Triggers Neurodegeneration

Number of pages: 74 Posted: 27 May 2021
Morgan Berard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas Martin Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A. Fon, Armen Saghatelyan and Abid Oueslati
Université Laval - CHU de Québec Research Center, Université Laval - Department of Molecular Medicine, Université Laval, Université Laval - CHU de Québec Research Center, Université Laval - CHU de Québec Research Center, Université Laval - CHU de Québec Research Center, Université Laval - Department of Molecular Medicine, Université Laval - CHU de Québec Research Center, Université Laval - Department of Molecular Medicine, Université Laval - Department of Molecular Medicine, Université Laval, Université Laval, Université Laval - CHU de Québec Research Center, McGill University, McGill University - McGill Parkinson Program and Neurodegenerative Diseases Group, McGill University, University of Colorado at Boulder - 6Department of Electrical, Computer, and Energy Engineering, Korea Advanced Institute of Science and Technology (KAIST), McGill University - The Neuro’s Early Drug Discovery Unit (EDDU), Université Laval - CHU de Québec Research Center, University of Victoria, Université Laval, Université Laval, Université Laval, McGill University, Université Laval and Université Laval - Department of Molecular Medicine
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Optobiology, protein aggregation, alpha-synuclein, Parkinson’s disease, cryptochrome 2, animal model, cell culture, iPSC-derived neurons, seeding, Lewy bodies