Macau University of Science and Technology - State Key Laboratory of Quality Research in Chinese Medicines, Jinan University - Department of Chemistry, Jinan University - Department of Chemistry, Macau University of Science and Technology - Department of Pathology, Jinan University - Department of Chemistry, Guangdong Medical University - Department of Clinical Immunology, Guangdong Medical University - Department of Clinical Immunology, Macau University of Science and Technology - State Key Laboratory of Quality Research in Chinese Medicines, Jinan University - Institute of Pharmaceutical Analysis and Guangdong Medical University - Department of Clinical Immunology