University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, Sanquin Research - Department of Immunopathology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, Amsterdam UMC, Vrije Universiteit - Department of Neurology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, University of Amsterdam - Department of Medical Microbiology and Infection Control, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, VU University Medical Center - Amsterdam Rheumatology and Immunology Center, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease, Sanquin Research - Department of Immunopathology, University of Amsterdam - Department of Rheumatology and Clinical Immunology, Amsterdam UMC, Vrije Universiteit - Department of Neurology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Sanquin Research - Department of Immunopathology and University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade

Leiden University - Willem-Alexander Children’s Hospital, Leiden University - Willem-Alexander Children’s Hospital, Erasmus University Rotterdam (EUR) - Department of Paediatric Nephrology, Tergooi Medical Center - Department of Paediatrics, University of Amsterdam - Department of Pediatric Pulmonology, Erasmus University Rotterdam (EUR) - Department of General Paediatrics, Erasmus University Rotterdam (EUR) - Department of Paediatric Intensive Care, University of Amsterdam - Department of Pediatric Pulmonology, Zaans Medical Centre - Department of Paediatrics, Radboud University Nijmegen - Section of Paediatric Infectious Diseases, University of Groningen - Department of Paediatric Rheumatology, Ommelander Hospital - Department of Paediatrics, Maastricht University - Department of Pediatrics, Canisius Wilhelmina Hospital - Department of Paediatrics, Academic Hospital Paramaribo - Department of Paediatrics, Alrijne Hospital - Department of Paediatrics, Isala Hospital - Department of Paediatrics, University of Amsterdam - Department of Paediatric Immunology, Rheumatology and Infectious Disease, BovenIJ Hospital - Department of Paediatrics, Elkerliek Hospital - Department of Paediatrics, Leiden University - Willem-Alexander Children’s Hospital, Utrecht University - Julius Center, Bravis Hospital - Department of Paediatrics, Meander Medical Centre - Department of Paediatrics, Erasmus University Rotterdam (EUR) - Department of Paediatric Infectious Diseases and Immunology, Groene Hart Hospital - Department of Paediatrics, ZorgSaam Hospital - Department of Paediatrics, Maasstad Hospital - Department of Paediatrics, University of Amsterdam - Department of Paediatric Immunology, Rheumatology and Infectious Disease, Amphia Hospital - Department of Paediatrics, Zuyderland Medical Centre - Department of Paediatrics, Leiden University - Willem-Alexander Children’s Hospital, Deventer Ziekenhuis - Department of Paediatrics, Spaarne Gasthuis Academy, Slingeland Hospital - Department of Paediatrics, Curaçao Medical Center - Department of Paediatrics, Martini Hospital - Department of Paediatrics, Erasmus University Rotterdam (EUR) - Department of Paediatric Intensive Care, Bernhoven - Department of Paediatrics, Academic Hospital Paramaribo - Department of Paediatrics, University of Amsterdam - Department of Paediatric Immunology, Rheumatology and Infectious Disease, University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease, Albert Schweitzer Hospital - Department of Paediatrics, University of Groningen - Department of Paediatric Rheumatology, Curaçao Medical Center - Department of Paediatrics, Curaçao Medical Center - Department of Paediatrics, Catharina Hospital - Department of Paediatrics, Elisabeth-Tweesteden Hospital - Department of Paediatrics, Maxima Medical Centre - Department of Paediatrics, Gelre Hospital - Department of Paediatrics, Haga Hospital - Department of Paediatrics, Radboud University Nijmegen - Department of Paediatric Intensive Care, Erasmus University Rotterdam (EUR) - Department of Paediatric Pulmonology, Haga Hospital - Department of Paediatrics, Admiraal De Ruyter Hospital - Department of Paediatrics, Leiden University - Willem-Alexander Children’s Hospital, Leiden University - Willem-Alexander Children’s Hospital, Maastricht University - Department of Pediatrics, Radboud University Nijmegen - Section of Paediatric Infectious Diseases, Dijklander Hospital - Department of Paediatrics, Princess Maxima Center for Pediatric Oncology, Franciscus Gasthuis & Vlietland - Department of Paediatrics, Maasstad Hospital - Department of Paediatrics, University Medical Centre Utrecht - Department of Paediatric Rheumatology,, Haga Hospital - Department of Paediatrics, Leiden University - Willem-Alexander Children’s Hospital, St Jansdal Hospital - Department of Paediatrics, Haaglanden Medical Center - Department of Paediatrics, Utrecht University - Department of Paediatric Infectious Diseases, Radboud University Nijmegen - Department of Pharmacology and Toxicology, Bravis Hospital - Department of Paediatrics, Leiden University - Willem-Alexander Children’s Hospital and Leiden University - Willem-Alexander Children’s Hospital

Imperial College London, affiliation not provided to SSRN, affiliation not provided to SSRN, Universidade de Santiago de Compostela - Genetics, Vaccines, Infections and Paediatrics Research group (GENVIP), affiliation not provided to SSRN, Imperial College London - Section of Paediatric Infectious Disease, Imperial College London, Imperial College London - Department of Epidemiology and Biostatistics, affiliation not provided to SSRN, Imperial College London, University of Liverpool, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, London School of Hygiene & Tropical Medicine - Medical Research Council Unit The Gambia, Imperial College London, affiliation not provided to SSRN, Erasmus University Rotterdam (EUR) - Department of Paediatric Infectious Diseases and Immunology, affiliation not provided to SSRN, Bern University Hospital, University of Bern, Imperial College London, Radboud University Nijmegen - Section of Paediatric Infectious Diseases, NHS Foundation Trust - Department of Paediatric Immunology, Infectious Diseases & Allergy, Royal Alexandra Hospital, University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease, affiliation not provided to SSRN, Erasmus University Rotterdam (EUR) - Department of General Paediatrics, University of Oxford - Oxford Vaccine Group, affiliation not provided to SSRN, University of Oxford - Oxford Vaccine Group, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Ludwig Maximilian University of Munich (LMU) - Division of Paediatric Infectious Diseases, London School of Hygiene & Tropical Medicine - Department of Clinical Research, affiliation not provided to SSRN, Medical University of Graz - Department of General Paediatrics, Imperial College London, University of Liverpool - Institute of Infection, Veterinary and Ecological Sciences, Imperial College London - Section of Paediatric Infectious Disease, Universidad Complutense de Madrid (UCM), affiliation not provided to SSRN, Imperial College London - Section of Paediatric Infectious Disease, Imperial College London - Section of Paediatric Infectious Disease and affiliation not provided to SSRN

University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Medical Microbiology and Infection Control, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, VU University Medical Center - Amsterdam Rheumatology and Immunology Center, VU University Amsterdam - Amsterdam Rheumatology and immunology Center, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease, Sanquin Research - Department of Immunopathology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Sanquin Research - Department of Immunopathology and University of Amsterdam - Amsterdam Rheumatology and Immunology Centre

University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Amsterdam UMC - Department of Neurology and Neurophysiology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, Amsterdam UMC - Department of Neurology and Neurophysiology, Sanquin Research - Department of Immunopathology, Amsterdam UMC, Vrije Universiteit - Department of Neurology, Amsterdam UMC, Vrije Universiteit - Department of Neurology, University of Amsterdam - Department of Gastroenterology and Hepatology, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Department of Neurology, University of Amsterdam - Department of Neurology, affiliation not provided to SSRN, University of Amsterdam - Department of Gastroenterology and Hepatology, University of Amsterdam - University Medical Center, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Internal Medicine, University of Amsterdam - Department of Internal Medicine, University of Amsterdam - Department of Internal Medicine, VU University Medical Center - Amsterdam Rheumatology and Immunology Center, University of Amsterdam - Department of Clinical Immunology and Rheumatology, University of Amsterdam - Department of Clinical Immunology and Rheumatology, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, University of Groningen - University Medical Center Groningen (UMCG), University of Groningen - Department of Rheumatology and Clinical Immunology, University of Groningen - Department of Dermatology, Leiden University - Department of Neurology, Leiden University - Department of Neurology, Leiden University - Department of Rheumatology, Leiden University - Department of Rheumatology, Leiden University - Department of Rheumatology, Leiden University - Department of Nephrology, Maastricht University - Division of Nephrology and Clinical Immunology, Department of Immunology, Maastricht UMC+, affiliation not provided to SSRN, Erasmus MC - Department of Neurology, Erasmus MC - Department of Neurology, Erasmus MC - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Dermatology, Erasmus University Rotterdam (EUR) - Department of Dermatology, Utrecht University - Brain Center Rudolf Magnus, Utrecht University - University Medical Center (Utrecht), University of Amsterdam - Department of Medical Microbiology and Infection Control, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, affiliation not provided to SSRN, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research, Sanquin Research - Department of Immunopathology, Sanquin Research, Sanquin Research, University of Amsterdam - University Medical Center, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre and Amsterdam UMC - Department of Neurology and Neurophysiology

Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, Sanquin Research - Department of Immunopathology, Amsterdam UMC - Department of Neurology and Neurophysiology, Amsterdam UMC - Department of Neurology and Neurophysiology, University of Amsterdam, Amsterdam UMC, Vrije Universiteit - Department of Neurology, Amsterdam UMC, Vrije Universiteit - Department of Neurology, University of Amsterdam - Department of Gastroenterology and Hepatology, University of Amsterdam - Department of Rheumatology and Clinical Immunology, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, Location Reade, University of Amsterdam - Amsterdam Rheumatology and Immunology Centre, University of Amsterdam - Department of Neurology, University of Amsterdam - Department of Neurology, affiliation not provided to SSRN, University of Amsterdam - Department of Gastroenterology and Hepatology, University of Amsterdam - University Medical Center, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Dermatology, University of Amsterdam - Department of Internal Medicine, University of Amsterdam - Department of Internal Medicine, University of Amsterdam - Department of Internal Medicine, VU University Medical Center - Amsterdam Rheumatology and Immunology Center, University of Amsterdam - Department of Clinical Immunology and Rheumatology, University of Amsterdam - Department of Clinical Immunology and Rheumatology, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM) - Centre for Infectious Disease Control, University of Groningen - University Medical Center Groningen (UMCG), University of Groningen - Department of Rheumatology and Clinical Immunology, University of Groningen - Department of Dermatology, Leiden University - Department of Neurology, Leiden University - Department of Neurology, Leiden University - Department of Rheumatology, Leiden University - Department of Rheumatology, Leiden University - Department of Rheumatology, Leiden University - Department of Nephrology, Maastricht University - Division of Nephrology and Clinical Immunology, Department of Immunology, Maastricht UMC+, Erasmus MC - Department of Neurology, Erasmus MC - Department of Neurology, Erasmus MC - Department of Neurology, Erasmus University Rotterdam (EUR) - Department of Dermatology, Erasmus University Rotterdam (EUR) - Department of Dermatology, Utrecht University - Brain Center Rudolf Magnus, Utrecht University - University Medical Center (Utrecht), Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, Sanquin Research, Sanquin Research, University of Amsterdam - University Medical Center, Sanquin Research - Department of Immunopathology, Sanquin Research - Department of Immunopathology, University of Amsterdam - University Medical Center, University of Amsterdam - University Medical Center, Amsterdam UMC - Department of Neurology and Neurophysiology and University of Amsterdam - Department of Pediatric Immunology, Rheumatology and Infectious Disease