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Albert R. La Spada

University of California, Irvine - Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, and the UCI Institute for Neurotherapeutics

SCHOLARLY PAPERS

2

DOWNLOADS

98

TOTAL CITATIONS

0

Scholarly Papers (2)

1.

Huntingtin Maintains Mitochondrial Genome Integrity and Function

Number of pages: 71 Posted: 18 Jun 2021
University of Texas Medical Branch-Galveston - Department of Neurology, University of Texas Medical Branch-Galveston - Department of Neurology, University of Texas Medical Branch-Galveston - Department of Neurology, Houston Methodist Research Institute, University of California, Irvine, University of Texas Medical Branch-Galveston - Department of Internal Medicine, University of California, Irvine, Duke University, University of Texas Medical Branch-Galveston - Department of Neuroscience, Cell Biology, and Anatomy, University of Texas Medical Branch-Galveston - Department of Neurology, University of Texas Medical Branch-Galveston - Department of Neurology, Sam Houston State University, University of Washington, Buck Institute for Research on Aging, Houston Methodist Research Institute, University of Texas Medical Branch-Galveston - Department of Internal Medicine, University of California, Irvine - Department of Pathology and Laboratory Medicine, University of California, Irvine, University of Texas Medical Branch-Galveston - Department of Neurology and University of Texas Medical Branch-Galveston - Department of Neurology
Downloads 59

Abstract:

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Microsatellite Repeat Instability; CAG triplet repeat expansions; Huntington’s disease; Huntingtin and mitochondrial genome maintenance; Poly-glutamine repeat expansions in huntingtin protein; Oxidative Stress and mitochondrial DNA damage; Mitochondrial DNA damage and mitochondrial dysfunction

2.

Skeletal Muscle Proteostasis Promotes Central Nervous System Rejuvenation and Reduced Neuroinflammation During Aging and Neurodegenerative Disease

Number of pages: 51 Posted: 19 May 2023
University of Southern California - Leonard Davis School of Gerontology, University of Southern California - Leonard Davis School of Gerontology, University of California, Irvine - Department of Pathology and Laboratory Medicine, University of Alabama at Birmingham - Comprehensive Diabetes Center, University of Alabama at Birmingham - Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham - Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham - Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham - Department of Neurology, University of California, Irvine - Department of Pathology and Laboratory Medicine, University of California, Irvine - Department of Pathology and Laboratory Medicine, Case Western Reserve University - Department of Genetics and Genome Sciences and University of Southern California - Leonard Davis School of Gerontology
Downloads 39

Abstract:

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aging, skeletal muscle, autophagy, Alzheimer's disease, TFEB