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David C. Stieg

Rowan University - Department of Molecular Biology

1 Medical Center Drive

Stratford, NJ 08084

United States

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Aberrant Cyclin C Nuclear Release Induces Mitochondrial Fragmentation and Dysfunction in MED13L Syndrome Fibroblasts

Posted: 25 Jun 2021
Kai-Ti Chang, Jan Jezek, David C. Stieg, Zachary A. Kiss, Kevin M. Kemper, Ping Jiang, Hyung-Ok Lee, Warren Kruger, Peter M. van Hasselt and Randy Strich
Rowan University - Department of Molecular Biology, Rowan University - Department of Molecular Biology, Rowan University - Department of Molecular Biology, Department of Medicine, Bassett Medical Center, Rowan University - Department of Molecular Biology, Rowan University - Department of Molecular Biology, Fox Chase Cancer Center, Fox Chase Cancer Center, University Utrecht Medical Center - Department of Metabolic and Endocrine Disease and Rowan University - Department of Molecular Biology

Abstract:

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Hypotonia, mitochondrial fragmentation, mitochondrial dysfunction, MED13L, pifithrin µ, haploinsufficiency