Ospedale dell'Angelo - Department of Cardiology, affiliation not provided to SSRN, Kerckhoff-Klinik GmbH, affiliation not provided to SSRN, affiliation not provided to SSRN, Heinrich Heine University Dusseldorf, Cantonal Hospital - Department of Cardiology, University of Copenhagen - Copenhagen University Hospital, University of Copenhagen - Copenhagen University Hospital, IRCCS Policlinico San Donato, affiliation not provided to SSRN, IRCCS Humanitas Research Hospital, affiliation not provided to SSRN, Alvaro Cunqueiro University Hospital - Cardiology Department, affiliation not provided to SSRN, GVM Care & Research - Anthea Hospital, affiliation not provided to SSRN, University of Turin - Department of Cardiology, University of Galway, University Hospital Galway, University of Hamburg - University Medical Center Hamburg-Eppendorf, affiliation not provided to SSRN, affiliation not provided to SSRN, Clinical Hospital San Carlos - Cardiovascular Institute, University of Catania, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Ospedale dell'Angelo - Department of Cardiology, Ospedale dell'Angelo - Department of Cardiology, Institut Universitaire de Cardiologie et de Pneumologie de Québec, IRCCS Humanitas Research Hospital, Humanitas University and GVM Care & Research - Maria Cecilia Hospital