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Andreas Wack

The Francis Crick Institute - Immunoregulation Laboratory

1 Midland Road

London, NW1 1AT

United Kingdom

  • The Francis Crick Institute - Immunoregulation Laboratory

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Scholarly Papers (1)

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Influenza A Virus Induces LDHA Expression and Lactate Formation to Inhibit Type I IFN and Promote Replication in Primary Human Airway Epithelium

Number of pages: 21 Posted: 02 Jul 2021
Jacob Thyrsted, Jacob Storgaard, Julia Blay-Cadanet, Anne Louise Hansen, Alexander Heinz, Anne Laugaard Thielke, Stefania Crotta, Frank de Paoli, David Olagnier, Andreas Wack, Karsten Hiller and Christian K. Holm
Aarhus University - Department of Biomedicine, Aarhus University - Department of Biomedicine, Aarhus University - Department of Biomedicine, Aarhus University - Department of Biomedicine, Technische Universität Braunschweig - Department of Bioinformatics and Biochemistry, Aarhus University - Department of Biomedicine, The Francis Crick Institute - Immunoregulation Laboratory, Aarhus University - Department of Biomedicine, Aarhus University - Department of Biomedicine, The Francis Crick Institute - Immunoregulation Laboratory, Technology University of Braunschweig - Department of Bioinformatics and Biochemistry and Aarhus University - Department of Biomedicine
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Abstract:

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Influenza A virus, SARS-CoV-2, immunometabolism, lactate, lactate dehydrogenase A, airway epithelium, type I interferon, MAVS, glycolysis, Krebs cycle