Istituto di Ricerche Farmacologiche Mario Negri IRCCS - Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Sapienza University of Rome - National Research Council (CNR) of Italy, Tobacco Free Research Institute (Ireland), Imperial College London, Prevention and Research Institute (ISPRO) - Oncologic Network, Agència de Salut Pública de Barcelona, Technical University of Cartagena (UPCT), Sapienza University of Rome - National Research Council (CNR) of Italy, University of Pavia - Department of Public Health, Experimental and Forensic Medicine, Government of the Community of Madrid - Pneumology Service, Institut Català d'Oncologia, Maastricht University, University of Crete, Institut Català d'Oncologia and Independent