Massachusetts Institute of Technology - Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology - Koch Institute for Integrative Cancer Research, University of Washington - Department of Biochemistry, University of Washington - Department of Biochemistry, Massachusetts Institute of Technology - Koch Institute for Integrative Cancer Research, Ragon Institute of MGH, MIT and Harvard, University of Washington - Department of Medicinal Chemistry, University of Washington - Department of Medicinal Chemistry, Ragon Institute of MGH, MIT and Harvard, University of Washington - Department of Biochemistry and Massachusetts Institute of Technology - Koch Institute for Integrative Cancer Research