Nanchang University - First Affiliated Hospital/Gaoxin Hospital, VA Puget Sound Health Care System - Geriatric Research Education and Clinical Center, University of Texas Health Science Center at Houston - Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston - Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston - Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston - Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston - Department of Medicine, Section of Oncology, VA Puget Sound Health Care System - Division of Medical Oncology, University of Washington - Department of Surgery, University of Washington - Department of Surgery, VA Puget Sound Health Care System - Geriatric Research Education and Clinical Center and University of Texas at Houston - Department of Integrative Biology and Pharmacology