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June Li

University of Toronto - Department of Laboratory Medicine and Pathobiology

Medical Sciences Building, 6th Floor

1 King's College Circle

Toronto, Ontario M5S 1A8

Canada

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c-Mpl-del, an Alternative Splicing Isoform of c-Mpl, Promotes Malignancy and Chemoresistance of AMKL by Regulating AKT/DDIT3 Survival Signaling

Number of pages: 48 Posted: 23 Aug 2021
Fei Li, Qiong Wang, Mo Yang, Maio Xu, Yiming Wang, Ting Xu, Junyu Huang, Xiaoqiong Gu, Li Zhang, Rui Sun, Xunsha Sun, Zuyong He, Nanyan Yang, Jingyao Li, Jinxin Ou, Xueying Huang, Yange Cao, Xin Zhao, Xiaohong Ruby Xu, Xiaohong Ruby Xu, Danielle Karakas, Danielle Karakas, June Li, Heyu Ni and Qing Zhang
Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - Seventh Affiliated Hospital, University of TorontoShandong University - Department of Hematology, University of Toronto - Department of Laboratory Medicine and Pathobiology, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Guangzhou Medical University, Guangzhou Medical University - Guangzhou Institute of Pediatrics, Sun Yat-sen University (SYSU) - State Key Laboratory of Oncology in South China, Sun Yat-sen University (SYSU) - National Key Clinical Department and Key Discipline of Neurology, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol, University of TorontoUniversity of Toronto - Department of Laboratory Medicine and Pathobiology, University of TorontoUniversity of Toronto - Department of Laboratory Medicine and Pathobiology, University of Toronto - Department of Laboratory Medicine and Pathobiology, University of Toronto - Department of Medicine and Sun Yat-sen University (SYSU) - State Key Laboratory of Biocontrol
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Abstract:

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c-Mpl; alternative splicing; acute megakaryocytic leukemia; proliferation; chemotherapy resistance