Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences - Peking Union Medical College, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Guangzhou Medical University - State Key Laboratory of Respiratory Disease, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases and Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Clinical Research Center of Cardiovascular Diseases