University of California, San Diego (UCSD) - Department of Pediatrics, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Shiga University of Medical Science, University of California, San Diego (UCSD) - Department of Pediatrics, affiliation not provided to SSRN, University of California, San Diego (UCSD) - Department of Pediatrics, affiliation not provided to SSRN, University of California, San Diego (UCSD) - Department of Pediatrics and affiliation not provided to SSRN