Dario Trapani

European Institute of Oncology (IEO) IRCCS

SCHOLARLY PAPERS

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Scholarly Papers (2)

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1.

A Conceptual Framework For Cautious Escalation Of Anticancer Treatment: How To Optimize Overall Benefit And Obviate The Need For De-Escalation Trials

Cancer Treatment Reviews, Vol 0, No. 0, March 2024 (Forthcoming)
Number of pages: 22 Posted: 03 May 2023 Last Revised: 08 Feb 2024
Ivan Pourmir, Hendrik Van Halteren, Reza Elaidi, Dario Trapani, Florian Strasser, Gerard Vreugdenhil and Mike Clarke
Universite Paris Descartes - Assistance Publique - Hôpitaux de Paris, Admiraal De Ruyter Hospital, Independent, European Institute of Oncology (IEO) IRCCS, University of Bern, Maxima Medical Centre and Queen's University Belfast - Centre for Public Health
Downloads 55 (749,697)

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clinical trials, methodology, overtreatment, de-escalation

2.

Effect of Age on Safety and Efficacy of Novel Cancer Drugs Investigated in Early-Phase Clinical Trials

Number of pages: 24 Posted: 17 May 2024
Eleonora Nicolò, Sara Gandini, Federica Giugliano, Jacopo Uliano, Oriana D’Ecclesiis, Stefania Morganti, Emanuela Ferraro, Dario Trapani, Paolo Tarantino, Paola Zagami, Laura Boldrini, Irene Caramella, Ambra Carnevale Schianca, Massimo Cristofanilli, Marzia Adelia Locatelli, Angela Esposito, Carmen Belli, Ida Minchella, Carmen Criscitiello, Antonio Marra and Giuseppe Curigliano
Cornell University - Weill Cornell Medicine, European Institute of Oncology (IEO) IRCCS, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Harvard University - Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, European Institute of Oncology (IEO) IRCCS, Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Cornell University - Weill Cornell Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and European Institute of Oncology (IEO) IRCCS - Division of New Drugs and Early Drug Development for Innovative Therapies
Downloads 19 (1,065,659)

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Cancer, solid tumors, age, elderly, phase I, early-phase clinical trial, new drugs, adverse events, Survival, outcome