Xiaoyun Lai

Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine

Shanghai

China

  • Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine

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NADPH Metabolism Determines the Leukemogenic Capacity and Drug Resistance of AML Cells

Number of pages: 57 Posted: 27 Sep 2021
Chiqi Chen, Xiaoyun Lai, Yaping Zhang, Li Xie, Zhuo Yu, Sijia Dan, Yu Jiang, Weicai Chen, Ligen Liu, Yi Yang, Dan Huang, Yuzheng Zhao and Junke Zheng
Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, East China University of Science and Technology (ECUST) - Optogenetics & Synthetic Biology Interdisciplinary Research Center, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, East China University of Science and Technology - Optogenetics & Synthetic Biology Interdisciplinary Research Center,, Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine, East China University of Science and Technology (ECUST) - Optogenetics & Synthetic Biology Interdisciplinary Research Center and Shanghai Jiao Tong University (SJTU) - Hongqiao International Institute of Medicine
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Abstract:

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NADPH metabolism, metabolic sensor, Acute myeloid leukemia, leukemia-initiating cells, endosteal niche, MTX resistance