Department of Human Genetics, The University of Chicago, Department of Human Genetics, The University of Chicago, University of Porto Rua Alfredo Allen, Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC) and Instituto de Inovação e Investigação em Saúde, University of Porto Rua Alfredo Allen, Division of Genetics and Genomics and Howard Hughes Medical Institute, Boston Children’s Hospital, Departments of Pediatrics and Neurology, Harvard Medical School, Department of Medical Genetics, University of Alberta, Spectrum Health - Helen DeVos Children's Hospital, Department of Clinical Genetics, Odense University Hospital, Department of Clinical Genetics, Odense University Hospital, Department of Human Genetics, The University of Chicago, Department of Human Genetics, The University of Chicago, Department of Human Genetics, The University of Chicago, Department of Human Genetics, The University of Chicago, Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC) and Instituto de Inovação e Investigação em Saúde, University of Porto Rua Alfredo Allen, University of Pennsylvania - Children's Hospital of Philadelphia, University of Pennsylvania - Children's Hospital of Philadelphia, Division of Genetics and Genomics and Howard Hughes Medical Institute, Boston Children’s Hospital, Departments of Pediatrics and Neurology, Harvard Medical School, Department of Neurosurgery, Pediatrics, and Cellular & Molecular Physiology, Yale School of Medicine, Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC) and Instituto de Inovação e Investigação em Saúde, University of Porto Rua Alfredo Allen, Division of Genetics and Genomics and Howard Hughes Medical Institute, Boston Children’s Hospital, Departments of Pediatrics and Neurology, Harvard Medical School and Department of Human Genetics, The University of Chicago; The Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior, The University of Chicago