Hannover Medical School - Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School - Department of Gastroenterology, Hepatology and Endocrinology, Technische Universität München (TUM), University of Hamburg - University Medical Center Hamburg-Eppendorf, Dresden University of Technology - University Clinic Carl Gustav Carus, Charité - Universitätsmedizin Berlin - Berlin Institute of Health, Oncodoc GmbH, HOPE—Practice for Oncology, HELIOS Hospital, Ludwig Maximilian University of Munich (LMU), Leopoldina Hospital Schweinfurt, Heidelberg University, HOPE—Practice for Oncology, HOPE—Practice for Oncology, HOPE—Practice for Oncology, Department of Hematology, Oncology and Gastroenterology, Maria Hilf Kliniken, University of Greifswald - University Hospital Greifswald, Institut für Klinisch-Onkologische Forschung Krankenhaus Nordwest Frankfurt/Main and Schleswig-Holstein University - University Medical Center

affiliation not provided to SSRN, affiliation not provided to SSRN, Maastricht University - GROW School for Oncology and Reproduction, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Leeds - School of Computing, Institut für Klinisch-Onkologische Forschung Krankenhaus Nordwest Frankfurt/Main, affiliation not provided to SSRN, University College London - MRC Clinical Trials Unit, Royal Marsden NHS Foundation Trust, University College London - MRC Clinical Trials Unit, Royal Marsden NHS Foundation Trust and Maastricht University - GROW School for Oncology and Reproduction