Hui-Kuan Lin

Wake Forest School of Medicine - Department of Cancer Biology

United States

  • Wake Forest School of Medicine - Department of Cancer Biology

SCHOLARLY PAPERS

2

DOWNLOADS

55

TOTAL CITATIONS

2

Scholarly Papers (2)

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1.

Discovery of Fused Benzimidazole-Imidazole Autophagic Flux Inhibitors for Treatment of Triple-Negative Breast Cancer

Number of pages: 12 Posted: 07 May 2022
Dong-Lin Yang, Ya-Jun Zhang, Jie Lei, Shi-qiang LI, Liu-jun He, Dian-yong Tang, Chuan Xu, Lingtian Zhang, Jingyuan Wen, Hui-Kuan Lin, Hong-yu Li, Zhongzhu Chen and Zhigang Xu
Chongqing University of Arts and Sciences, Chongqing University of Arts and Sciences, Chongqing University of Arts and Sciences, Chongqing University of Arts and Sciences, Chongqing University of Arts and Sciences, Chongqing University of Arts and Sciences, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Wake Forest School of Medicine - Department of Cancer Biology, affiliation not provided to SSRN, Chongqing University of Arts and Sciences and Chongqing University of Arts and Sciences
Downloads 36 (993,704)

Abstract:

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Benzimidazole-imidazole, Triple-negative breast cancer (TNBC), DNA repair, Antitumor activity, Autophagy

2.

Pyruvate Dehydrogenase Kinase Supports Macrophage NLRP3 Inflammasome Activation During Acute Inflammation

Number of pages: 44 Posted: 21 Oct 2021
Allison K. Meyers, Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Juan Liu, Rajesh K. Manne, Hui-Kuan Lin, Cristina M. Furdui, Jason W. Locasale, Charles McCall and Xuewei Zhu
Wake Forest School of Medicine - Department of Microbiology and Immunology, Wake Forest School of Medicine - Department of Internal Medicine, Wake Forest School of Medicine - Department of Internal Medicine, Wake Forest School of Medicine - Department of Internal Medicine, Wake Forest School of Medicine - Department of Internal Medicine, Duke University, Wake Forest School of Medicine - Department of Cancer Biology, Wake Forest School of Medicine - Department of Cancer Biology, Wake Forest School of Medicine - Department of Internal Medicine, Duke University, Wake Forest School of Medicine - Department of Microbiology and Immunology and Wake Forest University - Department of Internal Medicine
Downloads 19 (1,190,272)
Citation 2

Abstract:

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NLRP3 inflammasome, macrophages, sepsis, pyruvate dehydrogenase kinase, immunometabolism, mitochondria, cristae, autophagy, mitochondrial fission and fusion