Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) - Department of Infectious-Tropical Diseases and Microbiology, Prince Felipe Research Center - Genomics of Gene Expression Laboratory, University of Milano-Bicocca - School of Medicine and Surgery, University of Florida - Genetics Institute, Sacro Cuore Don Calabria Hospital - Department of Infectious, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale - Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, Sacro Cuore Don Calabria Hospital - Department of Infectious, MetabERN-University of Milano-Bicocca-Fondazione MBBM-Ospedale - Pediatric Departement and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, Negrar di Valpolicella - Department of Infectious Tropical diseases and Microbiology, Negrar di Valpolicella - Department of Infectious Tropical diseases and Microbiology, University of Milano-Bicocca - School of Medicine and Surgery, Milano-Bicocca University - Bicocca Center of Bioinformatics, Biostatistics and Bioimaging, University of Milano-Bicocca - Fondazione IRCCS San Gerardo dei Tintori, University of Florida, Prince Felipe Research Center - Genomics of Gene Expression Laboratory and University of Milano-Bicocca - Centre of Biostatistics for Clinical Epidemiology