University of Cologne - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), RWTH Aachen University - Institute of Pathology, University of Cologne - Department of Internal Medicine, University of Cologne - Immunology and Hygiene, University of Cologne - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne - Department of Internal Medicine, University of Cologne - Department of Internal Medicine, University of Cologne - Department of Internal Medicine, University of Cologne - Department of Internal Medicine, University of Wuerzburg - Institute for Hygiene and Microbiology, RWTH Aachen University Hospital - Institute of Pathology, University of Cologne - Department of Internal Medicine and University of Cologne - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD)