Tongji University - Institute for Regenerative Medicine, University of Miami - Diabetes Research Institute, University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology, University of North Carolina (UNC) at Chapel Hill - Department of Surgery, Sapienza University of Rome - Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology, North Carolina State University - Department of Molecular Biomedical Sciences, University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology, Sapienza University of Rome - Departments of Medico-Surgical Sciences and Biotechnologies, University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology, Sapienza University of Rome - Translational and Precision Medicine, Sapienza University of Rome - Translational and Precision Medicine, Sapienza University of Rome - Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome - Department of Movement, Human and Health Sciences, University of Utah - Department of Medicinal Chemistry, University of Miami - Diabetes Research Institute, University of North Carolina (UNC) at Chapel Hill - Department of Surgery, Cornell University - Department of Biomedical Sciences, North Carolina State University - Department of Clinical Sciences, North Carolina State University - Department of Molecular Biomedical Sciences, North Carolina State University - Department of Clinical Sciences, Tongji University - Institute for Regenerative Medicine, University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology and University of North Carolina (UNC) at Chapel Hill - Department of Cell Biology and Physiology