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Johan Botling

Uppsala University - Department of Immunology, Genetics and Pathology

SCHOLARLY PAPERS

4

DOWNLOADS

237

TOTAL CITATIONS

1

Scholarly Papers (4)

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1.

Spatial Immunophenotyping of the Tumor Microenvironment in Non-Small Cell Lung Cancer

Number of pages: 47 Posted: 16 Aug 2022
Max Backman, Carina Strell, Amanda Lindberg, Johanna Mattsson, Hedvig Elfving, Hans Brunström, Aine O'Reilly, Martina Bosic, Miklos Gulyas, Johan Isaksson, Johan Botling, Klas Kärre, Karin Jirström, Kristina Lamberg, Fredrik Ponten, Karin Leandersson, Artur Mezheyeuski and Patrick Micke
Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University, Lund University, Karolinska Institutet - Department of Oncology-Pathology, Uppsala University, Uppsala University, Uppsala University, Uppsala University - Department of Immunology, Genetics and Pathology, Karolinska Institutet - Department of Microbiology, Tumor and Cell Biology (MTC), Lund University - Division of Oncology and Pathology, Uppsala University - Uppsala University Hospital, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University - Department of Translational Medicine, Uppsala University - Department of Immunology, Genetics and Pathology and Uppsala University - Department of Immunology, Genetics and Pathology
Downloads 84 (790,029)

Abstract:

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Immune cell infiltration, multiplex imaging, checkpoint inhibitor therapy, tumor microenvironment, lung cancer, NSCLC, tumor infiltrating lymphocytes

2.

An Immune Score Reflecting Pro-and Anti-Tumoral Balance of Tumor Microenvironment Has Major Prognostic Impact and Predicts Immunotherapy Response in Solid Cancers

Number of pages: 43 Posted: 31 Aug 2022
Artur Mezheyeuski, Max Backman, Johanna Mattsson, Alfonso Martín-Bernabé, Chatarina Larsson, Ina Hrynchyk, Klara Hammarström, Simon Ström, Joakim Ekström, Siarhei Mauchanski, Salome Khelashvili, Amanda Lindberg, Margrét Agnarsdóttir, Per-Henrik Edqvist, Jutta Huvila, Ulrika Segersten, Per-Uno Malmström, Johan Botling, Björn Nodin, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Karin Leandersson, Bengt Glimelius, Anna Portyanko, Fredrik Ponten, Karin Jirström, Patrick Micke and Tobias Sjöblom
Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Karolinska Institutet - Department of Oncology-Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, City Clinical Pathologoanatomic Bureau, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, NN Alexandrov National Cancer Centre, NN Alexandrov National Cancer Centre, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Uppsala University - Department of Immunology, Genetics and Pathology, University of Turku - Department of Pathology, Uppsala University - Department of Surgical Sciences, Uppsala University - Department of Surgical Sciences, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Division of Diagnostic Radiology and Unilabs Mammography Unit, Lund University - Department of Translational Medicine, Uppsala University - Department of Immunology, Genetics and Pathology, NN Alexandrov National Cancer Centre, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University - Division of Oncology and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology and Uppsala University - Department of Immunology, Genetics and Pathology
Downloads 75 (844,901)

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tumor immunology, macrophages, immunoscore

3.

Vascular Leakage in Human Non-Small Cell Lung Cancer Predicts Immune Evasion and Poor Response to Immunotherapy

Number of pages: 38 Posted: 05 Sep 2024
Emmanuel Nwadozi, Carina Strell, Sofia Nordling, Max Backman, Sebastian Marwitz, Torsten Goldmann, Johan Isaksson, Johan Botling, Hans Brunström, Cecilia Lindskog, Patrick Micke, Lena Claesson-Welsh and Sneak Peek Administrator
Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, German Center for Infection Research (DZIF) - Clinical Tuberculosis Unit, German Center for Infection Research (DZIF) - Clinical Tuberculosis Unit, Uppsala University, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University, Uppsala University, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology and Independent
Downloads 44 (1,133,231)
Citation 1

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Vascular leakage, non-small cell lung cancer, survival, endothelial cell, tumor microenvironment, anti-tumor immunity, tertiary lymphoid structures, immunotherapy

4.

The Ratio of Cytotoxic Lymphocytes to M2-Like Macrophages is Prognostic in Immunogenic Tumors and Predicts Immunotherapy Response

Number of pages: 98 Posted: 02 Dec 2021
Artur Mezheyeuski, Max Backman, Johanna Mattsson, Alfonso Martín-Bernabé, Chatarina Larsson, Ina Hrynchyk, Klara Hammarström, Simon Ström, Joakim Ekström, Siarhei Mauchanski, Salome Khelashvili, Margrét Agnarsdóttir, Per-Henrik Edqvist, Jutta Huvila, Ulrika Segersten, Per-Uno Malmström, Johan Botling, Björn Nodin, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Karin Leandersson, Bengt Glimelius, Anna Portyanko, Fredrik Ponten, Karin Jirström, Patrick Micke and Tobias Sjöblom
Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Karolinska Institutet - Department of Oncology-Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, City Clinical Pathologoanatomic Bureau, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology, NN Alexandrov National Cancer Centre, NN Alexandrov National Cancer Centre, Uppsala University - Department of Immunology, Uppsala University - Department of Immunology, Genetics and Pathology, University of Turku - Department of Pathology, Uppsala University - Department of Surgical Sciences, Uppsala University - Department of Surgical Sciences, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Department of Clinical Sciences, Lund University - Division of Diagnostic Radiology and Unilabs Mammography Unit, Lund University - Department of Translational Medicine, Uppsala University - Department of Immunology, Genetics and Pathology, NN Alexandrov National Cancer Centre, Uppsala University - Department of Immunology, Genetics and Pathology, Lund University - Division of Oncology and Pathology, Uppsala University - Department of Immunology, Genetics and Pathology and Uppsala University - Department of Immunology, Genetics and Pathology
Downloads 34 (1,263,436)

Abstract:

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tumor immunology, macrophages, ImmunoScore