Mahidol University - Division of Infectious Diseases and Tropical Medicine, Mahidol University - Department of Pharmacology, Mahidol University - Department of Microbiology, Mahidol University - Department of Pharmacology, Mahidol University - Biomedical Research Incubator Unit, Mahidol University - Department of Immunology, Ministry of Public Health, Thailand - Department of Medical Sciences, University of Melbourne - Murdoch Children's Research Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Mahidol University - Siriraj Institute of Clinical Research (SICRES)