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Patricia Sheen

Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology

Lima

Peru

  • Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology

SCHOLARLY PAPERS

6

DOWNLOADS

273

TOTAL CITATIONS

0

Scholarly Papers (6)

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1.

Biorecognition of Antigens from Mycobacterium Tuberculosis Using a Sandwich ELISA Associated with Magnetic Nanoparticles

Number of pages: 49 Posted: 10 Dec 2021
León Janampa Nancy, Mirko Zimic, Svitlana Shinkaruk, Robert H. Gilman, Daniela E. Kirwan, Eric Fouquet, Magali Szlosek and Patricia Sheen
Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology, Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology, University of Bordeaux - The Institute of Molecular Sciences (ISM), Johns Hopkins University - Department of International Health, University of London - Institute of Infection and Immunity, University of Bordeaux - The Institute of Molecular Sciences (ISM), University of Bordeaux - The Institute of Molecular Sciences (ISM) and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 77 (823,616)

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active tuberculosis, immunoassay, magnetic nanoparticle, recombinant protein, polyclonal antibody, biofunctionalization.

2.

Alternative Cost-Effective Media to Facilitate MODS Culture for Diagnostics of Tuberculosis

Number of pages: 29 Posted: 31 Jan 2022
Patricia Sheen, Joseline Rodriguez, Roberto Alcántara, Johnny Vargas, Louis Grandjean, David Moore, Robert H. Gilman and Mirko Zimic
Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology, Universidad Peruana Cayetano Heredia, affiliation not provided to SSRN, affiliation not provided to SSRN, Children Hospital Lahore - Institute of Child Health, London School of Hygiene & Tropical Medicine, Johns Hopkins University - Department of International Health and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 53 (1,031,043)

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tuberculosis, MODS, diagnostics, culture media, irradiation, lyophilization

3.

Direct Nanopore amplicon sequencing from sputum reveals micro‑heteroresistance and mixed infections masked by culture in Mycobacterium tuberculosis

Number of pages: 46 Posted: 14 Jan 2026
Carlos Barrios-Tapia, Omar A. Romero-Rodriguez, Diego A. Taquiri-Diaz, Diego Ramos-Lette, Carla A. Apaza-Quiroz, Paul J. D. Avellaneda-Menéndez, Sonia Huamán, Robert H. Gilman, Louis Grandjean, Silvia Emperatriz Arévalo de los Ríos, Juan Ernesto Curto Chávez, Córdova Pisco Evelyn Genthell, Patricia Sheen and Mirko Zimic
Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, affiliation not provided to SSRN, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Ricardo Palma, Johns Hopkins University - Department of International Health, University College London - Department of Infection, Inflammation and Immunity, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 47 (1,170,409)

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Heteroresistance, Mycobacterium tuberculosis, Nanopore sequencing, lineages

4.

Evaluation of Powdered and Lyophilized Mods Media for Mycobacterium Tuberculosis Detection: A Stability and Performance Assessment

Number of pages: 38 Posted: 19 May 2025
Karen Lopez, Robert H. Gilman, Mirko Zimic and Patricia Sheen
affiliation not provided to SSRN, Johns Hopkins University, Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 35 (1,263,436)

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tuberculosis, diagnostics, culture, MODS, Microscopic Observed Drug Susceptibility, culture media, efficiency, contamination, drug resistance, drug susceptibility

5.

Heterologous Expression of Mycobacterium tuberculosis RpsA Sensitizes Mycobacterium smegmatis to Pyrazinamide: Implications for Drug Resistance

Number of pages: 41 Posted: 14 Jan 2026
Ricardo Antiparra, Marco Santos, Angie Toledo, Luis Vilca, Alen Zimic-Sheen, Belen Balta, Robert H. Gilman, Claudia Machicado, Patricia Sheen and Mirko Zimic
Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Universidad Peruana Cayetano Heredia, Johns Hopkins University, Universidad Peruana Cayetano Heredia - Laboratory of Translational Research and Computational Biology, Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 33 (1,277,121)

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tuberculosis, Pyrazinamide, pyrazinoic acid, PZA, POA, RpsA, Mycobacterium smegmatis, Mycobacterium tuberculosis, ribosome, Drug resistance

6.

Comparative Assessment of Decontamination and DNA Extraction Approaches to Optimize Mycobacterium tuberculosis DNA Yield and Minimize Human DNA from Sputum

Number of pages: 25 Posted: 14 Jan 2026
Jimena Ráez, Sonia Huamán, Candy León, Robert Gilman, Mirko Zimic and Patricia Sheen
affiliation not provided to SSRN, Universidad Ricardo Palma, Universidad Peruana Cayetano Heredia, Johns Hopkins University, Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology and Universidad Peruana Cayetano Heredia - Laboratory of Bioinformatics and Molecular Biology
Downloads 28 (1,345,526)

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DNA extraction, sputum treatment, DNA quantity, DNA quality, tuberculosis