Zhejiang University - Department of Big Data in Health Science, Zhejiang University - Department of Big Data in Health Science, Zhejiang University - Department of Big Data in Health Science, Zhejiang University - Department of Big Data in Health Science, Zhejiang University - Department of Colorectal Surgery and Oncology, Zhejiang University - National Clinical Research Center for Child Health, Sichuan University - West China School of Public Health, Chinese Academy of Medical Sciences - National Clinical Research Center for Cancer, Central South University - Department of Gastroenterology, Zhejiang University - Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province, University of Edinburgh - Western General Hospital, Department of Colorectal Surgery, University of Edinburgh - Edinburgh Cancer Research UK Centre, Zhejiang University - Department of Colorectal Surgery and Oncology and Zhejiang University - Department of Big Data in Health Science