University of Eastern Finland, University of Eastern Finland, Clinical Neuroimmunology Unit, Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele - Clinical Neuroimmunology Unit, University of Helsinki, University of Eastern Finland, University of Helsinki, University of Helsinki, University of Eastern Finland, University of Helsinki, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, University of Milan - Department of Pathophysiology and Transplantation and University of Helsinki