Shenzhen University, affiliation not provided to SSRN, Shenzhen University, affiliation not provided to SSRN, affiliation not provided to SSRN, King Abdulaziz University, King Abdulaziz University, Shenzhen University, Shenzhen University - Biobank, Shenzhen University, Health Science Center, First Affiliated Hospital, Shenzhen Second People's Hospital, Institute of Translational Medicine, affiliation not provided to SSRN, Ocean University of China and Shenzhen University - Key Laboratory of Optoelectronic Devices and Systems