Kaili University - School of Educational Science, University of Oxford - Nuffield Department of Medicine, Diabetes Research Unit, Cardiovascular Analytics Group, Hong Kong, China-UK Collaboration, University of North Carolina (UNC) at Chapel Hill - Project-China, King’s College London - Department of Biostatistics & Health Informatics, Diabetes Research Unit, Cardiovascular Analytics Group, Hong Kong, China-UK Collaboration, The Chinese University of Hong Kong (CUHK) - School of Life and Health Sciences, The University of Hong Kong, The University of Hong Kong - Department of Medicine, Tianjin Medical University - Department of General Surgery, Second Hospital of Tianjin Medical University - Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease and The University of Hong Kong - Division of Clinical Pharmacology and Therapeutics