National Taiwan University - Department of Internal Medicine, Independent, National Health Research Institutes, National Taiwan University, National Health Research Institutes, National Health Research Institutes, Independent, Independent, Independent, Academia Sinica, Independent, Independent, University of Chicago - Biological Sciences Division, National Taiwan University, Independent, Independent, I-Shou University - E-Da Hospital, Academia Sinica, Academia Sinica, Academia Sinica, Independent, Independent, Independent, National Taiwan University, National Health Research Institutes, Academia Sinica, Independent, National Taiwan University, National Taiwan University, Harvard University - Section on Integrative Physiology and Metabolism and National Taiwan University - Department of Internal Medicine